Polymer Release out of Spherical Vesicle through a Pore

Translocation of a polymer out of curved surface or membrane is studied via mean first passage time approach. Membrane curvature gives rise to a constraint on polymer conformation, which effectively drives the polymer to the outside of membrane where the available volume of polymer conformational fluctuation is larger. Considering a polymer release out of spherical vesicle, polymer translocation time τ is changed to the scaling behavior τ ∼ L2 for R < RG, from τ ∼ L 3 for R ≫ RG, where L is the polymer contour length and R, RG are vesicle radius and polymer radius of gyration respectively. Also the polymer capture into a spherical budd is studied and possible apparatus for easy capture is suggested. 36.20.Ey, 83.10.Nn, 05.40.+j Typeset using REVTEX 1